nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity

Chemical examination of the leaves of Styrax ferrugineus yielded 5-[3 "-(be ta -D-glucopyranosyloxy)propyl]-7-methoxy-2-(3',4'-dimethoxyphenyl) benzofu ran, along with the known nor-lignans 5-(3 " -hydroxypropyl)-7-methoxy-2-(3 ',4'-methylenedioxyphenyl)benzofuran, 5-(3 " -hydroxypropyl)-7-methoxy-2-(3 ',4'-dimethoxyphenyl)benzofuran, 5-[3 "-(beta -D-glucopyranosyloxy)propyl]- 7-methoxy-2- (3', 4'-methylenedioxyphenyl)benzofuran and the lignan, dihydr odehydrodiconiferyl alcohol. All arylpropanoids isolated showed antibacteri al and antifungal activities. The structures of the isolates were establish ed by spectroscopic analysis. (C) 2000 Elsevier Science Ltd. All rights res erved.