A 71 year old woman developed conjunctivitis, asymmetrical oligoarthritis,
and cystitis (Reiter's syndrome) secondary to intravesical BCG treatment fo
r transitional cell carcinoma of the bladder. She received oral prednisolon
e, izoniazid, and pyridoxine and made a full recovery. Increasing use of BC
G as immunotherapy will lead to an increase in the incidence of ECG associa
ted reactive arthritis. Prompt recognition and early diagnosis will. facili
tate treatment and recovery.