Seismic tomography models of the three-dimensional upper mantle velocity st
ructure of the Mediterranean-Carpathian region provide a better understandi
ng of the lithospheric processes governing its geodynamical evolution. Slab
detachment, in particular lateral migration of this process along the plat
e boundary, is a key element in the lithospheric dynamics of the region dur
ing the last 20 to 30 million years. It strongly affects arc and trench mig
ration, and causes along-strike variations in vertical motions, stress fiel
ds, and magmatism. In a terminal-stage subduction zone, involving collision
and suturing, slab detachment is the natural last stage in the gravitation
al settling of subducted lithosphere.