Despite having the lowest complication rate of all hemodialysis accesses, t
he prevalence of autologous arteriovenous (AV) fistulas has declined to 28%
in the United States. The reasons for this decline include high early AV f
istula failure rates, long maturation times, the frequent need for emergent
dialysis, unavailable or poor pre-ESRD programs and planning, patient resi
stance to the realities of impending ESRD, and financial disincentives to A
V fistula placement. Despite these barriers, programs throughout the countr
y have demonstrated the ability to increase AV fistula prevalence to more t
han 50%. The strategies employed have included increased reliance on upper
arm brachiocephalic and transposed basilic vein fistulas, the use of preope
rative imaging ti, identify the best sites for fistula creation, and aggres
sive attempts at salvage of nonmaturing fistulas. Other groups have systema
tically and successfully replaced failed grafts with upper arm brachiocepha
lic or bracheobasilic fistulas. These experiences clearly show that exceedi
ng the National Kidney Foundation Dialysis Outcomes Quality Initiative (NKF
-DOQI) goal of more than 50% fistula placement is achievable in the United
States. Declining numbers of AV fistulas are the result of a combination of
factors, including changes in our patient population and learned practice
patterns coupled with a failure of our delivery system to provide education
, timely referral, and incentives for fistula placement. Increasing AV fist
ula prevalence in the United States is achievable and will improve patient
outcomes and decrease the costs of ESRD.