Management of peritoneal and hepatic metastases from gastrointestinal stromal tumors

The management of peritoneal and hepatic metastases from gastrointestinal s tromal tumors is a challenging clinical problem. Currently available system ic therapeutic agents have very limited activity in this particular disease . Patients with disease confined to a single organ/region are therefore man aged either by surgery or regional therapy e.g. intraperitoneal therapy or hepatic arterial chemoembolization, whereas those with multiple sites of in volvement should be enrolled on experimental trials of new agents. (C) 2000 Elsevier Science Ltd. All rights reserved.