Aim. To examine correlation between platelet aggregation and the degree of
left ventricular hypertrophy (LVH) in patients with hypertrophic cardiomyop
athy (HC).
Material and methods. Routine clinical examination, ECG, echo-CG, measureme
nt of platelet aggregation, routine biochemical blood tests were made in 45
HC males and 15 healthy controls.
Results. HC patients were characterized with high induced and spontaneous p
latelet aggregation which increased with left ventricular myocardial mass.
In LVH, platelets were especially sensitive to the aggregation inductor U-4
6619, thromboxane A(2) analogue.
Conclusion. It is demonstrated that ther is a positive correlation between
platelet aggregation and the degree of LVH in HC patients.