CsOH-promoted chemoselective mono-N-alkylation of diamines and polyamines

Authors
Salvatore, RN Schmidt, SE Shin, SI Nagle, AS Worrell, JH Jung, KW
Citation
Rn. Salvatore et al., CsOH-promoted chemoselective mono-N-alkylation of diamines and polyamines, TETRAHEDR L, 41(50), 2000, pp. 9705-9708
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
50
Year of publication
2000
Pages
9705 - 9708
Database
ISI
SICI code
0040-4039(200012)41:50<9705:CCMODA>2.0.ZU;2-0
Abstract
Selective N-alkylation of diamines and polyamines was carried out using ces ium hydroxide, 4 Angstrom molecular sieves, and DMF. This protocol was high ly chemoselective, favoring mono-N-alkylation over overalkylations. (C) 200 0 Published by Elsevier Science Ltd.