Me. Jung et Cp. Lee, Use of the non-aldol aldol process in the synthesis of the C1-C11 fragmentof the tedanolides: use of lactol ethers in place of tetrahydrofurans, TETRAHEDR L, 41(50), 2000, pp. 9719-9723
The use of a lactol methyl ether 23 in place of the simple tetrahydrofuran
11 allows for the high yielding non-aldol aldol process to occur without co
ncomitant tetrahydropyran formation (cf 13) to give the desired product 24
in good yield. (C) 2000 Elsevier Science Ltd. All rights reserved.