Conversion of alpha,beta-unsaturated ketones into alpha-hydroxy ketones using an Mn-III catalyst, phenylsilane and dioxygen: acceleration of conjugate hydride reduction by dioxygen

Authors
Magnus, P Payne, AH Waring, MJ Scott, DA Lynch, V
Citation
P. Magnus et al., Conversion of alpha,beta-unsaturated ketones into alpha-hydroxy ketones using an Mn-III catalyst, phenylsilane and dioxygen: acceleration of conjugate hydride reduction by dioxygen, TETRAHEDR L, 41(50), 2000, pp. 9725-9730
Citations number
42
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
50
Year of publication
2000
Pages
9725 - 9730
Database
ISI
SICI code
0040-4039(200012)41:50<9725:COAKIA>2.0.ZU;2-E
Abstract
Treatment of a variety of alpha,beta -unsaturated ketones with Mn(dpm)(3) ( 3 mol%)/PhSiH3 (1.3 equiv.)/isopropyl alcohol/O-2, followed by reductive wo rk-up with P(OEt)(3) resulted in the formation of alpha -hydroxy-ketones. ( C) 2000 Elsevier Science Ltd. All rights reserved.