A straightforward synthesis of 4-substituted 3,4-dihydro-1H-2, 1, 3-benzothiadiazine 2,2-dioxides

Authors
Agejas, J Garcia-Navio, JL Lamas, C
Citation
J. Agejas et al., A straightforward synthesis of 4-substituted 3,4-dihydro-1H-2, 1, 3-benzothiadiazine 2,2-dioxides, TETRAHEDR L, 41(50), 2000, pp. 9819-9823
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
50
Year of publication
2000
Pages
9819 - 9823
Database
ISI
SICI code
0040-4039(200012)41:50<9819:ASSO43>2.0.ZU;2-7
Abstract
4-Substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 11 have be en efficiently prepared in two steps from the suphamide 9 by condensation o f anion II, derived from 9 by metal-halogen exchange, with aromatic and ali phatic aldehydes and cyclodehydration of the so-formed alcohols 10 under ac idic conditions. (C) 2000 Elsevier Science Ltd. All rights reserved.