Efficient electrochemical cleavage of N,N-dimethylaminosulfonyl-protected indoles

Authors
Largeron, M Farrell, B Rousseau, JF Fleury, MB Potier, P Dodd, RH
Citation
M. Largeron et al., Efficient electrochemical cleavage of N,N-dimethylaminosulfonyl-protected indoles, TETRAHEDR L, 41(49), 2000, pp. 9403-9406
Citations number
17
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
49
Year of publication
2000
Pages
9403 - 9406
Database
ISI
SICI code
0040-4039(200012)41:49<9403:EECONI>2.0.ZU;2-L
Abstract
Indoles protected at the N-1 position with the N,N-dimethylaminosulfonyl gr oup were efficiently deprotected by electrolysis. Yields were in the 80-90% range and the method was compatible with a number of functional groups (ni trile, ester, chloride, carboxamide). (C) 2000 Elsevier Science Ltd. All ri ghts reserved.