Use of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide mimics in SH2 antagonists

Authors
Davidson, JP Martin, SF
Citation
Jp. Davidson et Sf. Martin, Use of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide mimics in SH2 antagonists, TETRAHEDR L, 41(49), 2000, pp. 9459-9464
Citations number
38
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
49
Year of publication
2000
Pages
9459 - 9464
Database
ISI
SICI code
0040-4039(200012)41:49<9459:UO1CAC>2.0.ZU;2-W
Abstract
Novel conformationally constrained phosphotyrosine pseudopeptide derivative s of the tetrapeptide pY-E-E-I were prepared and evaluated as SH2 binding a ntagonists. (C) 2000 Elsevier Science Ltd. All rights reserved.