Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain

Authors
Boger, DL Aquila, BM Tse, WC Searcey, M
Citation
Dl. Boger et al., Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain, TETRAHEDR L, 41(49), 2000, pp. 9493-9498
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
49
Year of publication
2000
Pages
9493 - 9498
Database
ISI
SICI code
0040-4039(200012)41:49<9493:SAEOAN>2.0.ZU;2-P
Abstract
The synthesis and evaluation of a bithiazole ester analogue of deglycobleom ycin A(2) that addresses the importance of the bithiazole-L-threonine amide for efficient DNA cleavage is described. (C) 2000 Elsevier Science Ltd. Ai l rights reserved.