Enantioselective synthesis of 5-substituted pipecolic acids using an intramolecular allylsilane-iminium ion cyclization

Authors
Cellier, M Gelas-Mialhe, Y Husson, HP Perrin, B Remuson, R
Citation
M. Cellier et al., Enantioselective synthesis of 5-substituted pipecolic acids using an intramolecular allylsilane-iminium ion cyclization, TETRAHEDR-A, 11(19), 2000, pp. 3913-3919
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
19
Year of publication
2000
Pages
3913 - 3919
Database
ISI
SICI code
0957-4166(20001006)11:19<3913:ESO5PA>2.0.ZU;2-0
Abstract
The application of the intramolecular allylsilane-iminium ion cyclization r eaction for the enantioselective synthesis of piperidine derivatives is des cribed. The synthetic potential of this methodology is demonstrated by the enantioselective synthesis of 5-substituted pipecolic acids. (C) 2000 Elsev ier Science Ltd. All rights reserved.