Case report: Carcinoma of the extraorbital lacrimal gland in a female Fischer 344 rat

A large subcutaneous mass was observed at necropsy in the right neck area o f a 95-week-old female Fischer 344 rat that served as an untreated control animal in a 2-year carcinogenicity study. Formalin-fixed, paraffin-embedded sections of the mass were stained with hematoxylin and eosin along with th e immunohistochemical biomarkers lactoperoxidase, catalase, and amylase. Ba sed on its histomorphological and immunohistochemical features, the lesion was diagnosed as a carcinoma of the extraorbital lacrimal gland.