Background. Hyperkalaemia is a common metabolic disorder; if left untr
eated it can lead to life-threatening consequences. We conducted this
study to determine the common aetiological factors for hyperkalaemia i
n hospital inpatients. Methods. This prospective cross-sectional study
was conducted in a referral teaching hospital in south India. One hun
dred and forty-three patients with hyperkalaemia (>5 mEq/L) were selec
ted on 20 random week days over a 3-month period. Ail the patients wer
e clinically and biochemically evaluated for the aetiology of hyperkal
aemia. Results. Hyperkalaemia was twice as common amongst males. Potas
sium supplementation and drugs were the leading causes for hyperkalaem
ia, with renal failure being a distant second. Hyperkalaemia developed
after admission to hospital in more than 75% of the patients. Severe
hyperkalaemia (>6 mEq/L) was seen in one-third of the patients. Conclu
sion Potassium supplementation and other iatrogenic conditions lead to
hyperkalaemia in inpatients. Males are at increased risk for hyperkal
aemia.