Ssc. Chang et al., TRANSRECTAL ULTRASOUND-GUIDED MANIPULATION OF THE CANINE PROSTATE WITH MINIMUM INTERVENTION, Laboratory animals, 31(3), 1997, pp. 219-224
The canine prostate is a widely used and well established animal model
for the assessment of therapeutic effects of laser technology in the
search for better options for the treatment of benign prostatic hyperp
lasia. Conventionally for such experiments, the canine prostate is app
roached by laparotomy or transperineal urethrotomy. We have demonstrat
ed a technique involving the use of ultrasound guided biopsy of the li
ver and prostate, and percutaneous laser treatment of the prostate, wh
ich has proved to be effective in reducing adverse effects on the expe
rimental animals but without compromising scientific requirements for
the experiments. We conclude that state-of-the-art percutaneous proced
ures not only refine animal intervention significantly but are also te
chnically feasible for most laser studies using the canine prostate as
an experimental model in the live animal.