A 5-year-old Hereford cow was donated to Oregon State University, College o
f Veterinary Medicine, Two weeks before presentation the cow was treated by
a left flank laparotomy to correct a uterine torsion that revealed an exce
ssive amount of abdominal fluid and a full term dead fetus. Ultrasonographi
c evaluation of the right cranioventral thoracic cavity was performed owing
to physical examination (muffled heart sounds, areas of silence) and thora
cocentesis findings suggestive of pleuritis, Ultrasonography revealed hypoe
choic pleural effusion and a mass of mixed echogenicity visible within the
right atrial lumen extending into the cranial vena cava, A diagnosis of cra
nial vena cava thrombosis was demonstrated at necropsy, The clinical, ultra
sonographic, and pathological features of this less common condition (crani
al vena cava thrombosis) in cattle are discussed.