Diagnostic and prognostic role of myoglobin in patients with suspected acute coronary syndrome

Citation
Tv. Stork et al., Diagnostic and prognostic role of myoglobin in patients with suspected acute coronary syndrome, AM J CARD, 86(12), 2000, pp. 1371
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
86
Issue
12
Year of publication
2000
Database
ISI
SICI code
0002-9149(200012)86:12<1371:DAPROM>2.0.ZU;2-S
Abstract
In patients with suspected acute coronary syndrome, myoglobin is, according to IFCC and NACB guidelines, the marker of choice for early determination of acute infarction, in particular in combination with creatine kinase-MB, 4 hours after admission with a sensitivity of 96%, and correctly excludes Q -wave infarctions. In patients without acute myocardial infarction, a posit ive troponin T (relative risk 31.5%), but not an elevated myoglobin (relati ve risk 4.5%), is highly predictive for adverse in-hospital outcome.