Both atenolol and propranolol blunt the fibrinolytic response to exercise but not resting fibrinolytic potential

Authors
Fernhall, B Szymanski, LM Gorman, PA Kamimori, GH Kessler, CM
Citation
B. Fernhall et al., Both atenolol and propranolol blunt the fibrinolytic response to exercise but not resting fibrinolytic potential, AM J CARD, 86(12), 2000, pp. 1398
Citations number
19
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
86
Issue
12
Year of publication
2000
Database
ISI
SICI code
0002-9149(200012)86:12<1398:BAAPBT>2.0.ZU;2-U
Abstract
This randomized, double-blind trial found that tissue plasminogen activator activity increased and plasminogen activator inhibitor-1 activity decrease d significantly more with exercise during placebo treatment than during tre atment with beta blockade. These results suggest that beta blockade blunts the fibrinolytic response to maximal exercise.