Purpose: To compare the effectiveness of Prevident 5000 Plus (5,000 ppm F)
and Colgate Winterfresh Gel (1100 ppm F) to arrest root carious lesions, Ma
terials and Methods: 201 subjects with at least one root carious lesion wer
e recruited from dental school patients. They were randomly assigned to use
either Prevident 5000 Plus (5000 ppm F) or Colgate Winterfresh Gel (1100 p
pm F) as sodium fluoride in the same silica base. Measurements of lesion ha
rdness, area, distance from the gingival margin, cavitation and plaque were
recorded at baseline and after 3 months by a single examiner. Results: Aft
er 3 months 38% of subjects using Prevident 5000 Plus and 10% using Winterf
resh Gel had one or more lesions that had become hard (P< 0.001). Non-cavit
ated lesions at baseline were more likely to become hard than cavitated les
ions. Compared to the Winterfresh group there was significant increase in t
he distance from the base of the lesion to the gingival margin and plaque s
cores were reduced in those using Prevident 5000 Plus.