Community-acquired pneumonia (CAP) affects approximately 1% of the pop
ulation annually. Initial antimicrobial therapy is most often empirica
l. Guidelines designed in other countries for the empirical management
of CAP are not recommended for use in Argentina. Studies from other c
ountries were considered together with unpublished local data to defin
e the potential etiologic microorganisms and their antimicrobial susce
ptibility. Recommended diagnostic tests, groups of patients for differ
ent therapies and hospitalization criteria were defined. Severe CAP re
quiring intensive care was distinguished from the rest because of its
distinct spectrum of etiologic agents and its high mortality, requirin
g a more focused therapy, Age, coexisting conditions and severity of i
llness were taken into account in the election of therapy.