Central composite design and optimization by multiresponse analysis of octacalcium phosphate synthesis

Authors
Heughebaert, JC Lebugle, A Vu, F Phan-Tan-Luu, R
Citation
Jc. Heughebaert et al., Central composite design and optimization by multiresponse analysis of octacalcium phosphate synthesis, ANALUSIS, 28(7), 2000, pp. 571-574
Citations number
10
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALUSIS
ISSN journal
03654877 → ACNP
Volume
28
Issue
7
Year of publication
2000
Pages
571 - 574
Database
ISI
SICI code
0365-4877(200009)28:7<571:CCDAOB>2.0.ZU;2-L
Abstract
Synthesis of octacalcium phosphate (OCP) by hydrolysis of brushite was stud ied using a 3 block central composite design including 4 factors and 6 resp onses. Analysis of the responses. Analysis of the responses allowed the def inition of one set of experimental conditions in which OCP was obtained wit h the highest overall desirability (87.6 %).