Laryngeal sarcoidosis: Treatment with the antileprosy drug clofazimine

Sarcoidosis is a chronic systemic granulomatous disease that occasionally a ffects the larynx. When the larynx is affected, the symptoms are frequently mild, but severe airway obstruction can occur. Although systemic corticost eroids are helpful, patients may become refractory to further drug administ ration. The current methods of treatment are here summarized, and the patie nt literature is reviewed. We also report a case of a young patient sufferi ng from laryngeal sarcoidosis successfully treated by the antileprosy agent clofazimine and propose it as an alternative treatment of laryngeal sarcoi dosis in patients refractory to corticosteroids.