Primary localized extranodal Hodgkin disease of the transverse colon

Extranodal Hodgkin disease presenting as a primary localized neoplasm is un common, with rare case reports describing primary sites other than lymph no des. The gastrointestinal tract is the most frequent site of involvement by extranodal Hodgkin disease, typically involving the stomach or small bowel . To date, we have been able to find only one fully documented case of Hodg kin disease of the sigmoid colon confirmed by immunohistochemical studies. We report a case of extranodal Hodgkin disease involving the transverse col on, presenting as inflammatory bowel disease and documented by light micros copic, immunohistochemical, cytogenetic, and molecular studies.