Solid-phase synthesis of 2,3-disubstituted indoles: Discovery of a novel, high-affinity, selective h5-HT2A antagonist

Authors
Smith, AL Stevenson, GI Lewis, S Patel, S Castro, JL
Citation
Al. Smith et al., Solid-phase synthesis of 2,3-disubstituted indoles: Discovery of a novel, high-affinity, selective h5-HT2A antagonist, BIOORG MED, 10(24), 2000, pp. 2693-2696
Citations number
17
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
24
Year of publication
2000
Pages
2693 - 2696
Database
ISI
SICI code
0960-894X(200012)10:24<2693:SSO2ID>2.0.ZU;2-I
Abstract
The application of a novel solid-phase synthesis of 2,3-disubstituted indol es utilizing a carbamate indole linker is described resulting in the identi fication of the novel, high-affinity, selective h5-HT2A antagonist 19. (C) 2000 Elsevier Science Ltd. All rights reserved.