Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia

Authors
Petty, EM Yanik, GA Hutchinson, RJ Alter, BP Schmalstieg, FC Levine, JE Ginsburg, D Robillard, JE Castle, VP
Citation
Em. Petty et al., Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia, J PEDIAT, 137(6), 2000, pp. 882-886
Citations number
19
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
137
Issue
6
Year of publication
2000
Pages
882 - 886
Database
ISI
SICI code
0022-3476(200012)137:6<882:SBMTIA>2.0.ZU;2-T
Abstract
Early death in Schimke immune-osseous dysplasia often results from renal Fa ilure and/or cell-mediated immunodeficiency. Kidney transplants have improv ed renal function, but effective therapy for the immunodeficiency has not y et been reported. We describe markedly improved marrow function 2 years aft er bone marrow transplantation in a boy with Schimke immunoosseous dysplasi a.