Potentiometric biosensor for urinary glucose level monitoring

Monitoring of urinary glucose level is of great interest in health control. As a fast and accurate means to achieve this purpose, a potentiometric glu cose biosensor based on SnO2 film was developed. The optimum manufacturing conditions and the functional characteristics of the biosensor were establi shed. The n-type Sb-doped SnO2 semiconductor film properties were character ized using electrochemical impedance spectroscopy. Measurements on urine sa mples yielded results that are in good agreement with those obtained with t he Nylander method and more accurate that those obtained with a test paper. Taking into account that urine samples do not need pretreatment and that b y the renewal of the enzyme membrane the stability period of the biosensor may be prolonged over 8 days, it may be used in continuous flux, too. (C) 2 000 John Wiley & Sons, Inc.