Citation
Sp. Jones et Dj. Lefer, Myocardial reperfusion injury: Insights gained from gene-targeted mice, NEWS PHYSL, 15, 2000, pp. 303-308
Citations number
10
Categorie Soggetti
Physiology
Journal title
NEWS IN PHYSIOLOGICAL SCIENCES
ISSN journal
08861714
→ ACNP
Volume
15
Year of publication
2000
Pages
303 - 308
Database
ISI
SICI code
0886-1714(200012)15:<303:MRIIGF>2.0.ZU;2-J
Abstract
Myocardial ischemia-reperfusion injury involves activation of multiple cell
types, including leukocytes and endothelial cells. The pursuant inflammati
on involves diminished nitric oxide production, influx of neutrophils, and
myocardial cell injury. Gene-targeted animals provide important clues about
the progression of this inflammatory cascade.