We reviewed our 10-year experience in skin metastases from lung cancer. We
identified a total of 26 patients with 49 resected skin metastases. Skin me
tastases were synchronous in 6 patients, 3 of whom underwent primary simult
aneous resection, and solitary in 6 (6/26=23.07%). Negative prognostic fact
ors were primary non-resectability (p=0.001), small cell lung cancer (p=0.0
32), simultaneous discovery of other cutaneous (p=0.048) or extracutaneous
(p=0.0005, Wald test p<0.002, Odds ratio = 14.37) metastases. Skin metastas
is represented the unique distant localization in almost one quarter of our
cases that represent the best-survivor category: in these patients skin me
tastasectomy is justified.