Citation
Y. Cui et Wh. Wong, Multiple-sequence information provides protection against mis-specified potential energy functions in the lattice model of proteins, PHYS REV L, 85(24), 2000, pp. 5242-5245
Citations number
36
Categorie Soggetti
Physics
Journal title
PHYSICAL REVIEW LETTERS
ISSN journal
00319007
→ ACNP
Volume
85
Issue
24
Year of publication
2000
Pages
5242 - 5245
Database
ISI
SICI code
0031-9007(200012)85:24<5242:MIPPAM>2.0.ZU;2-L
Abstract
The neutral nets in the lattice models of proteins are composed of a group
of similar sequences that encode for the same native structure. The maximal
neutral nets in an HP and an AB lattice model are investigated by exhausti
ve enumeration in the conformation space. The result demonstrates that the
performance of mis-specified potential functions can be improved significan
tly by averaging over sequences in the neutral nets.