ENANTIOMERIZATION BARRIERS BY DYNAMIC HPLC - STATIONARY-PHASE EFFECTS

Authors
GASPARRINI F MISITI D PIERINI M VILLANI C
Citation
F. Gasparrini et al., ENANTIOMERIZATION BARRIERS BY DYNAMIC HPLC - STATIONARY-PHASE EFFECTS, Tetrahedron : asymmetry, 8(12), 1997, pp. 2069-2073
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
12
Year of publication
1997
Pages
2069 - 2073
Database
ISI
SICI code
0957-4166(1997)8:12<2069:EBBDH->2.0.ZU;2-K
Abstract
Chiral atropisomeric naphthamides have been used as model compounds to investigate solute interconversion phenomena in free solution and dur ing liquid chromatography on a chiral stationary phase; energy barrier s measured in the mobile phase (thermal racemization of enriched sampl es) are 0.3-1.3 Kcal/mol lower than those measured in the stationary p hase (computer simulation). (C) 1997 Elsevier Science Ltd.