A novel porous chitosan/gelatin scaffold for tissue engineering was prepare
d via polyelectrolyte complex formation, freeze drying and post-crosslinkin
g with glutaraldehyde. The porosity and mean pore diameters could be contro
lled within 30 similar to 100 mum by varying the original water content and
the freezing conditions. Dipping the scaffolds in poly(lactic acid) provid
ed good mechanical properties making it a promising candidate towards tissu
e engineering. (C) 2000 Society of Chemical Industry.