A case of basal cell carcinoma of the skin in a patient with systemic sclerosis

A 46-year-old man complained of pain and stiffness in both hands. Most of h is fingertips were shortened, and Raynaud's phenomenon was evident. The ski n on his face and hands was hard and taut. An ulcerating mass measuring 3.2 x 2.5 cm was found on his left infraorbital area. Biopsy revealed basal ce ll carcinoma. Antinuclear antibody and anti-topoisomerase I antibody were s trongly positive. A high-resolution computed tomography (CT) scan of the lu ngs revealed interstitial fibrosis. Esophageal manometry showed low lower e sophageal sphincter pressure and gastroesophageal reflux. Under the diagnos is of basal cell carcinoma accompanying systemic sclerosis (SSc), surgical excision of the mass was performed, and immunosuppressant and vasodilator t herapies were conducted.