A facile method for nucleophilic aromatic substitution of cyclic amine

The expeditious solventless nucleophilic aromatic substitution using microw aves is described. A non-conventional synthetic procedure has been develope d where basic alumina has been used as energy transfer medium under Microwa ve Irradiation (MWI). The results were compared with those obtained by the classical method. This rapid and environmentally benign method avoids the u se of excess solvents and toxic bases usually employed in the process make this procedure very attractive for synthesis.