Novel thiazolidine derivatives as chiral catalysts in the enantioselectiveaddition of diethylzinc to aldehydes

Authors
Meng, QL Li, YL He, Y Guan, YD
Citation
Ql. Meng et al., Novel thiazolidine derivatives as chiral catalysts in the enantioselectiveaddition of diethylzinc to aldehydes, TETRAHEDR-A, 11(21), 2000, pp. 4255-4261
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
21
Year of publication
2000
Pages
4255 - 4261
Database
ISI
SICI code
0957-4166(20001103)11:21<4255:NTDACC>2.0.ZU;2-A
Abstract
New chiral thiazolidine derivatives were synthesized conveniently from natu ral L-cysteine and showed good enantioselectivity (up to 90% ee) in the add ition of diethylzinc to aldehydes. The catalytic efficiency of the thiazoli dine derivatives is influenced by the different structures of the thiazolid ine rings and the bulkiness of R moiety in the ester groups. (C) 2000 Elsev ier Science Ltd. All rights reserved.