Chronic systemic (hepatosplenic) candidiasis in a patient with granulocytic sarcoma

Citation
Vp. Gangadharan et al., Chronic systemic (hepatosplenic) candidiasis in a patient with granulocytic sarcoma, AM J CL ONC, 23(6), 2000, pp. 562-563
Citations number
7
Categorie Soggetti
Oncology
Journal title
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
ISSN journal
02773732 → ACNP
Volume
23
Issue
6
Year of publication
2000
Pages
562 - 563
Database
ISI
SICI code
0277-3732(200012)23:6<562:CS(CIA>2.0.ZU;2-Z
Abstract
Chronic systemic (hepatosplenic) candidiasis (CSC) is a syndrome of invasiv e candidiasis characterized by fever without localizing signs or symptoms. It occurs predominantly in patients with acute leukemia, after prolonged se vere neutropenia. We report a young woman who underwent extensive chemother apy for granulocytic sarcoma of the ovary; CSC then developed in this patie nt. She was successfully treated with fluconazole and liposomal amphoterici n B. Clinical presentation, diagnostic problems, and the current successful treatment with fluconazole and liposomal amphotericin B are discussed.