Use of topical cyclosporin for conjunctival manifestations of actinic prurigo

PURPOSE: To report the successful treatment of conjunctival manifestations of actinic prurigo with topical cyclosporin. METHODS: A 12-year-old female with extensive limbal lesions and chronic con junctivitis secondary to actinic prurigo was treated with topical cyclospor in, and a rapid clinical response was observed. RESULTS: The patient had the limbal lesions surgically excised. The lesions completely recurred over the first 2 postoperative months. Treatment with topical steroids and vitamin A ointment was unsuccessful. The patient was t hen treated with cyclosporine 2% drops and a dramatic improvement occurred. Over a 3-month period, the lesions completely resolved. CONCLUSION: Cyclosporine eyedrops may be an effective treatment for the con junctival manifestations of actinic prurigo. (C) 2000 by Elsevier Science I nc. All rig-hts reserved.