Ion channel behavior of supported bilayer lipid membranes on a glassy carbon electrode

Citation
Zy. Wu et al., Ion channel behavior of supported bilayer lipid membranes on a glassy carbon electrode, ANALYT CHEM, 72(24), 2000, pp. 6030-6033
Citations number
17
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL CHEMISTRY
ISSN journal
00032700 → ACNP
Volume
72
Issue
24
Year of publication
2000
Pages
6030 - 6033
Database
ISI
SICI code
0003-2700(200012)72:24<6030:ICBOSB>2.0.ZU;2-T
Abstract
A new kind of solid substrate, a glassy carbon (GC) electrode, was selected to support lipid layer membranes. On the surface of the GC electrode, we m ade layers of didodecyldimethylammonium bromide (a synthetic lipid). From e lectrochemical impedance experiments, we demonstrated that the lipid layers on the GC electrode were bilayer lipid membranes. We studied the ion chann el behavior of the supported bilayer lipid membrane. In the presence of per chlorate anions as the stimulus and ruthenium(II) complex cations as the ma rker ions, the lipid membrane channel was open and exhibited distinct chann el current. The channel was in a closed state in the absence of perchlorate anions.