Coronary spastic angina induced by anticholinesterase medication for myasthenia gravis - A case report

Myasthenia gravis (MG) is characterized by weakness of skeletal muscles bec ause of a decrease in the number of available acetylcholine receptors at ne uromuscular junctions. Anticholinesterase medication is widely used to trea t MG, but muscarinic side effects sometimes appear and limit the drug usage . To their knowledge, the authors present the first case of coronary spasti c angina quite possibly induced by anticholinesterase medication to treat M G. The appearance of coronary spastic angina in the present case is likely mediated through the increase of acethylcholine by anticholinesterase medic ation.