Nitrofurantoin is active against vancomycin-resistant enterococci

Authors
Zhanel, GG Hoban, DJ Karlowsky, JA
Citation
Gg. Zhanel et al., Nitrofurantoin is active against vancomycin-resistant enterococci, ANTIM AG CH, 45(1), 2001, pp. 324-326
Citations number
17
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
1
Year of publication
2001
Pages
324 - 326
Database
ISI
SICI code
0066-4804(200101)45:1<324:NIAAVE>2.0.ZU;2-A
Abstract
The activity of nitrofurantoin was tested against 300 isolates of Enterococ cus faecium, Enterococcus faecalis, and Enterococcus gallinarum. No isolate s tested were resistant to nitrofurantoin (MIC, greater than or equal to 12 8 mug/ml), including vancomycin-resistant E. faecium isolates with vanA- an d vanB-positive genotypes and vancomycin-resistant E. gallinarum isolates. We conclude that nitrofurantoin may provide effective treatment of urinary tract infections caused by vancomycin-resistant enterococci.