In vitro antibiotic susceptibility of Neisseria gonorrhoeae in Jakarta, Indonesia

Antibiotic susceptibilities were determined for 122 Neisseria gonorrheae is olates obtained from 400 sex workers in Jakarta, Indonesia, and susceptibil ities to ciprofloxacin, cefuroxime, cefoxitin, cefotaxime, ceftriaxone, chl oramphenicol, and spectinomycin were found. All isolates were resistant to tetracycline. A number of the isolates demonstrated decreased susceptibilit ies to erythromycin (MIC greater than or equal to 1.0 mug/ml), thiamphenico l (MIC greater than or equal to 1.0 mug/ml), kanamycin (MIC greater than or equal to 16.0 mug/ml), penicillin (MIC greater than or equal to 2.0 mug/ml ), gentamicin (MIC greater than or equal to 16.0 mug/ml), and norfloxacin ( MIC = 0.5 mug/ml). These data showed that certain antibiotics previously us ed in the treatment of gonorrhea are no longer effective.