Optimization of a fixed-bed bioreactor used in wastewater treatment is addr
essed. The objective of optimization is to maximize the treatment efficienc
y of the biofilter by manipulating the feed flow rate while satisfying oper
ational constraints. Numerical results indicate that the optimal input is c
haracterized as being on the boundary of the admissible region. Thus, the c
haracterized optimal solution is implemented using a simple feedback contro
l law, which provides the optimal input profile despite variations in subst
rate inlet concentration and biomass growth rate. (C) 2001 John Wiley & Son
s, Inc.