Based on Schmidt's ( 1975) variability of practice hypothesis, this study e
xamined acquisition and transfer of a gross motor skill, namely tossing, in
58 patients with Alzheimer's disease (AD) and 58 healthy older adults unde
r constant, blocked, and random practice conditions. While healthy older ad
ults were able to learn the tossing task equally well under the three pract
ice conditions, only AD patients receiving constant practice showed signifi
cant improvements. Tests of intermediate transfer yielded the expected rand
om practice advantage in healthy controls but not AT) patients. None of the
practice conditions facilitated intermediate transfer in AD patients; howe
ver, constant practice did benefit these impaired individuals on tests of n
ear transfer. These results indicate that the variability of practice hypot
hesis does not extend to AD patients. As motor learning and transfer were c
learly a function of constant practice, future attempts to retrain basic ac
tivities of daily living in AD patients should emphasize consistency in tra
ining, (C) 2000 Academic Press.