Spinal epidural abscesses in children: A 15-year experience and review of the literature

Citation
Jj. Auletta et Cc. John, Spinal epidural abscesses in children: A 15-year experience and review of the literature, CLIN INF D, 32(1), 2001, pp. 9-16
Citations number
59
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
32
Issue
1
Year of publication
2001
Pages
9 - 16
Database
ISI
SICI code
1058-4838(20010101)32:1<9:SEAICA>2.0.ZU;2-C
Abstract
We reviewed medical records and laboratory and diagnostic evaluations for 8 pediatric patients with spinal epidural abscesses who were treated during the last 15 years at our institution. Staphylococcus aureus was isolated fr om 5 of 8 epidural abscesses, including 2 abscesses with methicillin-resist ant S. aureus. Unusual isolates were group B Streptococcus in a patient wit h chronic vesicouretral reflux associated with the posterior urethral valve s and Aspergillus flavus in a patient with acute myelogenous leukemia. An a nalysis incorporating our results and a review of the English-language lite rature about abscesses in children and adults revealed differences related to age. Abscesses in children were more posterior in epidural location, had greater spinal column extension, and were associated with more favorable c linical outcomes than were abscesses in adults. Magnetic resonance imaging is the diagnostic procedure of choice; however, radionuclide bone scans sho uld be considered for associated distant osteomyelitis in children. Prompt diagnosis and combined medical and surgical treatment remain the cornerston es for the prevention of adverse outcomes.