Reactogenicity and immunogenicity of a Lyme disease vaccine in children 2-5 years old

Authors
Beran, J De Clercq, N Dieussaert, I Van Hoecke, C
Citation
J. Beran et al., Reactogenicity and immunogenicity of a Lyme disease vaccine in children 2-5 years old, CLIN INF D, 31(6), 2000, pp. 1504-1507
Citations number
8
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
31
Issue
6
Year of publication
2000
Pages
1504 - 1507
Database
ISI
SICI code
1058-4838(200012)31:6<1504:RAIOAL>2.0.ZU;2-B
Abstract
Two doses of a recombinant Lyme disease vaccine (15 and 30 mug) were admini stered to children 2-5 years old (0-1-month schedule) and were well tolerat ed. Both doses were highly immunogenic with geometric mean titers 1 month a fter vaccination of 4366 and 9877 ELISA units (EU)/mL, respectively. Nearly all subjects had antibody levels of greater than or equal to 1400 EU/mL, s uggesting protective tick titre for one tick season.