M. Radisic et al., Severe acute lung injury caused by Mycoplasma pneumoniae: Potential role for steroid pulses in treatment, CLIN INF D, 31(6), 2000, pp. 1507-1511
Published evidence of pathogenetic mechanisms of acute respiratory distress
syndrome (ARDS) in mycoplasmal lung infections suggests that the pulmonary
injury is related to a cell-mediated immune response. Therefore, steroids
may play a role in the treatment of severe cases. We describe a patient who
had Mycoplasma pneumoniae pneumonia that progressed to severe ARDS requiri
ng mechanical ventilation and who had improvement with prednisolone pulses.