Purpose. To evaluate the intraocular pressure (IOP) with three different in
struments, Goldmann applanation tonometer (GAT), noncontact tonometer, and
Tone-Pen after photorefractive keratectomy (PRK) for myopia. Methods. A pro
spective case series study to evaluate preoperative and postoperative IOP m
easurements of 149 eyes at 12 months. We performed GAT, noncontact tonometr
y, Tone-Pen central, and Tone-Pen temporal periphery measurements. We also
performed measurements of the central corneal thickness (CCT) by ultrasonic
pachymetry and keratometry. Preoperative IOP reading served as control for
all studies. Results. After PRK, IOP reading was significantly reduced in
the treated eyes when compared with the control measurements (11.87 +/- 1.7
3 vs. 13.37 +/- 1.52 mmHg, p < 0.0001 with GAT; 12.07 +/- 1.6 vs. 13.51 +/-
1.59 mmHg, p < 0.0001 with noncontact tonometer; 12.18 +/- 1.6 vs. 13.48 /- 1.55 mmHg, p < 0.0001 with Tone-Pen central; 13.48 +/- 1.65 vs. 13.71 +/
- 1.56 Hg, p < 0.0104 with Tono-Pen temporal periphery). There was also a s
ignificant correlation between IOP reading changes measured by GAT, noncont
act tonometer, Tone-Pen central, and change of CCT and between reduction of
IOP reading and keratometry (r(2) > 0.39, p < 0.0001 for each). The correl
ation between IOP reading change by Tone-Pen temporal periphery and CCT was
also significant but r(2) value was only 0.034. Tone-Pen temporal peripher
y postoperative IOP measurements had the best correlation with preoperative
GAT IOP (r(2) = 0.57, p < 0.0001). Conclusions, PRK reduced IOP reading as
measured by GAT, noncontact tonometer, and Tone-Pen central; less so when
measured by Tone-Pen temporal periphery. Early detection of glaucoma and IO
P follow-up in glaucoma patients may be done best by peripheral Tone-Pen me
asurements over the nonablated cornea.