A CASE OF JUVENILE ANKYLOSING-SPONDYLITIS AND CROHNS-DISEASE

Juvenile ankylosing spondylitis (JAS) is a chronic inflammatory arthri tis of the peripheral and axial skeleton, frequently accompanied by en thesitis. About four percent of patients with JAS have ulcerative coli tis or Crohn's disease. Crohn's disease is the more common of the two and is diagnosed in 26 percent of patients with chronic spondyloarthro pathy. In this paper, a 14-year-old male patient is presented as a typ ical case of juvenile ankylosing spondylitis and Crohn's disease with low back pain, morning stiffness, limited motion in anterior and Later al flexion and extension, left sacroiliitis, ankylosis in the apophyse al joints of the Lumbar vertebrae, abdominal pain, bloody diarrhea, ch aracteristic histopathologic changes of colonic involvement such as ly mphoid follicles, fissures, submucosal polymorphonuclear cell infiltra tion and definite ganglion cells. The current therapy with mesalazin, having fewer side effects than sulfosalazin, and its applicability in combination with naproxen sodium is also discussed.