Neuroblastoma and bronchogenic cyst: A rare association

A few of the known associations between paediatric cancer and congenital an omalies are attributable to contiguous-gene syndromes. Neuroblastoma (NB) h as been linked with an excess of gastrointestinal malformations, but there is a significant scarcity of associated respiratory anomalies. We report on two children having an abdominal NE and a bronchogenic cyst diagnosed simu ltaneously and in different order of appearance. Both masses were removed i n separated procedures, taking into account the priority and the time seque nce of chemotherapy. Literature is reviewed, checking that the genetic basi s for this association is supported by speculations about the oncogene RON.